Research Program on
Batch Manufacturing of Pharmaceuticals and Chemicals (BMPC)
May 2008 Consortium Meeting
Date: May 29, 2008
Place: Conference Room, Sophia Gordon Hall - East
15 Talbot Ave, Medford, MA 02155
Final Meeting Agenda
08:45 Coffee & Registration
09:00 –
09:15 Welcome
Dr. Christos Georgakis, Director, Systems Research Institute, Tufts
University
09:15 –
10:00 “Process Modeling Approaches in Pharmaceutical
Development”
Dr. David J. am Ende, Chemical R&D/Engineering Technology, Pfizer Inc.
10:00 –
10:30 “Tendency Modeling and Operability: Tools in Solving PAT,
QbD and Design Space Puzzles”
Dr. Christos Georgakis, Director, Systems Research Institute, Tufts
University
10:30 – 11:00 Break
11:00 –
11:30 “Optimization of Hydrogenation Reactions using Structural
Tendency Modeling Methods”
Foteini Makrydaki, PhD Candidate, Tufts University, Systems Research Institute
11:30 –
12:00 "Patient Specific Pharmacokinetic Modeling: The Challenge"
Dan Hines, PhD Candidate, Tufts University, Systems Research Institute
12:00 – 01:00 Lunch
01:00 –
01:30 “Operability of Non-Linear Processes”
Lin Li, Graduate Student, Tufts University, Systems Research Institute
01:30 –
02:15 “Embryo Coagulation: A Theory for Understanding Nucleation
of Polymorphic and Chiral Crystallizations”
Dr. Gregory Botsaris, Research Professor of Chemical Engineering, Tufts
University
02:15 - 02:45 Break
02:45 -
03:15 “Measuring and Modeling the Shape and Size Evolution of
Crystals”
Andrew Fiordalis, Graduate Student, Tufts University, Systems Research
Institute
03:15 –
03:35 “Modeling Particle Size Distributions with the General
Gamma Distribution”
Andrew Hagger, Undergraduate Student, Tufts University, Systems Research
Institute
03:35 – 04:30 General Discussion and Feedback
04:30 Adjournment
5.28.08